Mitigating security of supply risks in PHC monitoring

The most common method used by scientists to monitor host cell protein (HCP) levels in biological products is the enzyme immunoassay (ELISA). For the reagent, security of supply is a regulatory requirement ⁠—it is an essential factor to continuously monitor HCP during organic production. In this webinar, we explain why security of supply is important, the consequences of not having it, and how to mitigate this risk.

Topics Covered

  • Why security of supply is essential to your HCP plans
  • Consequences of not securing upstream supply
  • How to mitigate risk by securing supply distribution
  • Differences between antisera lot and ELISA lot


Joe Hirano, PhD, is Imaging and Western Blotting Program Manager at Cytiva based in Uppsala, Sweden, where he manages products and their applications between research and development and external collaborators to support customers. Since joining the company in 2000, Joe has worked with genomics, protein research and biomanufacturing products including electrophoresis, western blot, imaging and upstream bioprocessing products and downstream. His current focus is on the analysis of host cell proteins and other impurities. Prior to joining the biopharmaceutical industry, Joe studied marine biology as a research scientist.

David Chimento, PhD, is Vice President of the Custom Services Division at Rockland Immunochemicals, based in Limerick, Pennsylvania, USA. David coordinates and oversees research and development assignments for internal and external stakeholders, with a focus on project design and strategy for clients. David joined Rockland Immunochemicals in 2008 and worked on critical reagent development and assay development. He is particularly interested in creating tools for traditional and emerging biotherapy and biofabrication. One of his current areas of interest is the bioprocessing and analysis of host cell proteins and other impurities. Prior to joining the biotechnology industry, David studied microbiology and molecular biophysics with a focus on protein structure and protein-protein interactions.

Click here to register for this webinar.

Source link

Comments are closed.